A Natural Compound with Powerful Health Benefits Berberine is a natural plant compound found in herbs such as barberry, goldenseal, and Oregon grape. For centuries, it has been used in traditional medicine, but modern research is now uncovering the scientific mechanisms behind its remarkable health benefits. From supporting metabolic health to promoting cardiovascular and gut wellness, berberine is a versatile supplement that works at the cellular level. One of the key ways berberine works is by activating AMP-activated protein kinase (AMPK) , often referred to as the body’s “metabolic master switch.” AMPK regulates energy usage and helps balance glucose and fat metabolism. By activating this enzyme, berberine improves insulin sensitivity, supports healthy blood sugar levels, and encourages efficient energy use in the body. Berberine also has antioxidant and anti-inflammatory properties , which help protect cells from oxidative stress and chronic inflammation. These effects contr...