What Is Creatine and How Does It Work in the Body? Creatine is a naturally occurring compound found in the body, primarily in the muscles, and it plays a crucial role in energy production, especially during high-intensity, short-duration activities like weightlifting, sprinting, or explosive movements. Where Does Creatine Come From? Creatine is made up of three amino acids : arginine, glycine, and methionine. Your body can synthesize it in the liver, kidneys, and pancreas. You also get creatine through dietary sources , particularly from red meat and fish. However, to achieve performance-enhancing levels, many people take it as a supplement in the form of creatine monohydrate. How Does Creatine Work in the Body? Once in the body, creatine is converted into phosphocreatine and stored in your muscles . This stored form acts as a rapid energy reserve. Here’s a simplified breakdown of how it works: ATP: Your Body's Energy Currency During any activity, your muscles use adenosine...