What to Do if a CBD Patch Causes Irritation CBD patches are a convenient, steady way to get cannabidiol into your system, but like any skin product, they can sometimes irritate. If that happens, don’t panic. Most reactions are mild and manageable with a few simple steps. This post walks you through immediate first aid, how to judge severity, likely causes, prevention, and when to see a healthcare professional. Immediate steps (what to do right away) Remove the patch — gently peel it off and discard. Don’t try to “let it finish” if your skin is stinging, burning, or blistering. Wash the area — use lukewarm water and a mild, fragrance-free soap to remove adhesive residue and any product on the skin. Pat dry with a clean towel. Cool the skin — apply a cool (not ice-cold) compress for 10–15 minutes to ease itching and inflammation. Avoid scratching or picking — this reduces the risk of infection and scarring. Skip other topical products for the site until you know what caused the react...