Signs and Symptoms of High Uric Acid Levels High uric acid levels in the blood, a condition known as hyperuricemia, can occur when the body produces too much uric acid or fails to eliminate enough of it through urine. While it doesn’t always cause noticeable problems, elevated uric acid can lead to painful and potentially serious health conditions like gout, kidney stones, or kidney disease. Recognizing the early signs and symptoms can help prevent complications. Common Signs and Symptoms of High Uric Acid Joint Pain and Swelling (Gout Attacks) One of the most noticeable symptoms is sudden and intense joint pain, often in the big toe, but it can affect the ankles, knees, elbows, wrists, or fingers. This pain can: Come on, suddenly (often at night) Be severe and throbbing The last several days to a week You may also notice: Swelling Redness Warmth in the affected joint Joint Stiffness Even after a gout attack subsides, some people experience joint stiffness and discomfort during m...