Berberine Supports Healthy Blood Vessel Flexibility Healthy blood vessels are essential for overall cardiovascular health . As we age or face lifestyle stressors, blood vessels can become stiff, leading to higher blood pressure, reduced circulation, and increased risk of heart disease. Berberine, a natural compound found in plants like barberry and goldenseal, may help maintain blood vessel flexibility and support a healthy circulatory system. Berberine works by activating AMPK (adenosine monophosphate-activated protein kinase), a key enzyme that helps regulate cellular energy and improve endothelial function. The endothelium, the thin layer lining blood vessels, plays a crucial role in keeping arteries flexible and responsive. Additionally, berberine has anti-inflammatory and antioxidant properties that protect blood vessel walls from oxidative stress and inflammation, common contributors to stiffness and reduced elasticity. By improving endothelial health and reducing inflammati...