Berberine is Called Nature’s Metabolic Support Berberine, a bioactive compound found in plants like barberry, goldenseal, and Oregon grape, has earned the nickname “Nature’s Metabolic Support” for good reason. For centuries, it has been used in traditional Chinese and Ayurvedic medicine, and modern research is now confirming its powerful benefits for metabolic health. One of berberine’s standout features is its ability to activate AMP-activated protein kinase (AMPK), often referred to as the body’s “metabolic master switch.” This enzyme helps regulate how the body uses energy, promoting better balance in blood sugar, cholesterol, and fat metabolism. By supporting AMPK, berberine encourages the body to use glucose more efficiently and reduces insulin resistance, two major factors in maintaining healthy metabolic function. Studies suggest that berberine can: Support blood sugar control by helping cells take in glucose more effectively. Promote healthy cholesterol levels by lowering LDL ...