How Berberine Supports Metabolism and Fat-Burning Berberine, a natural plant compound found in herbs like Berberis , has gained attention for its ability to support metabolism and promote fat-burning. By activating key biological pathways, berberine helps regulate energy balance, improve fat metabolism, and enhance weight management. Here’s how it works: Activates AMPK – The Metabolic Master Switch Berberine activates an enzyme called AMP-activated protein kinase (AMPK), which plays a crucial role in regulating metabolism. Often referred to as the "metabolic master switch," AMPK: Enhances cellular energy production Increases fat oxidation Improves insulin sensitivity Supports glucose metabolism By turning on AMPK, berberine encourages the body to use stored fat for energy, helping with fat-burning and weight management. Regulates Blood Sugar and Insulin Sensitivity Stable blood sugar levels are essential for a healthy metabolism. Berberine helps regulate glucose levels ...